Projects

Explainable deep-learning for brain-machine interfaces
Explainable deep-learning for brain-machine interfaces

The motivation for this project arose from a critical challenge in brain-machine interface (BMI) technology: balancing the high performance of deep-learning models with the explainability and safety required for real-world applications. Current state-of-the-art deep-learning decoders excel in decoding brain activity for tasks like speech and movement but function as “black boxes,” posing risks in sensitive applications like controlling prosthetic limbs. Our goal was to explore whether KalmanNet—a hybrid model combining Kalman filter principles with deep-learning flexibility—could achieve both high performance and interpretability in BMI systems. To test this hypothesis, we designed a BMI experiment using data from two non-human primates performing dexterous finger movements (see video above). We compared KalmanNet’s decoding performance against traditional Kalman filters and advanced deep-learning algorithms, including LSTM and tcFNN models. KalmanNet uniquely integrates recurrent neural networks to dynamically adjust trust between neural inputs and dynamic predictions, leveraging explainability while achieving flexible performance. We evaluated these models both offline (on pre-recorded data) and online (real-time task execution), focusing on metrics like prediction accuracy, task completion rates, and path efficiency. The results showed that KalmanNet matched or exceeded the performance of deep-learning decoders in most metrics while retaining its explainable structure. Offline, KalmanNet achieved prediction accuracies comparable to the leading LSTM model. Online, it outperformed simpler models like the Kalman filter in terms of task completion rates and movement smoothness, demonstrating its capability to operate in real-time scenarios. However, we also found that KalmanNet, like other decoders, struggled with generalization in new task contexts and exhibited sensitivity to out-of-distribution noise, highlighting areas for further optimization. This work has been accepted for publication at NeurIPS 2024, and is available here.

Dec 29, 2024

Brain and muscle synergies for brain-machine interface decoding
Brain and muscle synergies for brain-machine interface decoding

The inspiration for this project stemmed from the need to improve brain-machine interface (BMI) performance, particularly in decoding complex multi-degree-of-freedom (DoF) movements. While the brain handles high-DoF tasks effortlessly, current BMI systems struggle to match this level of control. Our study was motivated by the hypothesis that the brain simplifies high-DoF tasks through synergies, functional groupings of muscles and neural activities. By examining whether these synergies could enhance decoding in implanted BMIs, we aimed to uncover strategies to bridge the gap between natural and artificial control.

Dec 28, 2024

Ankle impedance reliability
Ankle impedance reliability

In this project, I explored how reliably we can measure the mechanical impedance of the ankle during standing and walking. We used a custom-built robotic platform and motion capture setup, and measured the ankle torque and angle response to small perturbations (example perturbation shown in gif above). The goal was evaluating how reliably we can measure impedance parameters such as stiffness, damping and inertia, as an accurate and reliable measurement can help as a clinical metric as well as to develop biomimetic prostheses and exoskeletons.

Feb 1, 2024

Open-source web application for motor learning research
Open-source web application for motor learning research

The motivation for this project was to address significant barriers in procedural skill learning research. Traditional motor learning experiments require controlled lab environments, which limit sample size, accessibility, and diversity. Inspired by the need for more inclusive and scalable research methods, I developed an open-source online platform. This platform democratizes access to motor learning studies by removing coding prerequisites and simplifying experimental setup, making cutting-edge research feasible for a broader audience.

Mar 1, 2023

High-Five: open-source myoelectric upper-limb prosthesis
High-Five: open-source myoelectric upper-limb prosthesis

I developed High-Five, the first Chilean upper-limb myoelectric prosthesis (shown in the image above), which uses surface EMG electrodes to control a five-degree-of-freedom (DoF) robotic hand. This project aimed to provide a functional, accessible, and open-source solution for individuals requiring upper-limb prosthetics.

Dec 31, 2020